A Guide to Becoming an Oncology Nurse Practitioner

oncology nurse adjusting patient iv

Oncology Nurse Career Overview

Where you’ll work: Hospitals, cancer centers, palliative care centers, extended-care facilities, physician offices and clinics, home health and hospices.

What you’ll do: Provide care to cancer patients through chemotherapy, immunotherapy and other methods. Oncology nurses may act as a liaison between the patient and their care team.

Minimum degree required: ADN or BSN, but it’s common for employers to require that nurses have at least a BSN.

Who it’s a good fit for: The field of oncology is ever-changing as we continue to learn about how to treat cancer. An oncology nurse should want to keep learning as the field evolves. Since there is no cure for cancer, oncology nurses must be emotionally resilient as they encounter patients that may be fighting for their life.

Job perks: As an oncology nurse, you may get to be a part of cutting-edge cancer treatments.

Opportunities if you pursue a higher degree or certification: Getting certified as an Oncology Certified Nurse (OCN) is not required, but can demonstrate your expertise in the field and make you a more competitive job applicant. There are several other oncology nurse certifications as well, including Certified Pediatric Oncology Nurse (CPON), Certified Breast Care Nurse (CBCN) and more.

Median annual salary: $81,220

Oncology nurses care for cancer patients as they receive treatment. This specialty can be intense and demands a lot of compassion and resilience.

How to Become an Oncology Nurse in 5 Steps

Use these steps as a guide to pursue a career in oncology nursing, a specialty that involves working with patients and their families and as a member of a healthcare team.

Decide if oncology nursing is right for you.

nurse speaking with patient in scarf

Working with patients with serious or life-threatening illnesses requires a high level of emotional intelligence and mental stamina.

Determine what education you’ll need.

student nurse taking instruction from instructor

You’ll need to earn either an Associate Degree in Nursing (ADN) or a Bachelor of Science in Nursing (BSN). Online programs are available.

Graduate from an accredited nursing program.

four graduating students standing in line in caps and gowns

Earning a degree from an accredited program will qualify you to take the required licensing exam.

Get licensed as a registered nurse (RN).

nurse comforting older man in chair

With passing results from the licensing exam, you’ll be ready to apply for licensure with your state board of nursing.

Consider earning an oncology nurse certification.

nurse administering chemo via IV to older patient

Advanced certifications can help you move up in your career and make you a more competitive job applicant.

What Do Oncology Nurses Do?

Oncology nurses provide care to cancer patients through chemotherapy, immunotherapy, and other treatments. Their patients may be newly diagnosed, transitioning from cancer patient to cancer survivor, or have a terminal illness. Oncology nurses often serve as the point person and liaison between patients and other medical staff. 

An oncology nurse’s patients may be newly diagnosed, transitioning from cancer patient to cancer survivor, or have a terminal illness.

Responsibilities of an Oncology Nurse

An oncology nurse has many roles. They are caregivers, educators, navigators, healthcare coordinators, and more. Their main responsibilities include:

  • Administering chemotherapy, radiation, and immunotherapy treatments
  • Tracking patient responses to treatment and medication
  • Educating patients and their loved ones on treatment protocols and expectations 
  • Collaborating with healthcare professionals on care plans and a patient’s progress
  • Serving as a nurse navigator to connect patients to clinical and community resources
  • Conducting research to enhance the quality of care
  • Staying up to date on the latest research and innovations in oncology care

Is Oncology Nursing a Good Fit for You?

Due to the sensitive nature of their work, oncology nurses should be natural caregivers, compassionate and able to adapt to challenging situations. Here are some skills and traits that can help an oncology nurse succeed.

  • Knowledge seeker. The field of oncology is complex and constantly changing, and an oncology nurse should have the desire to continue learning as the field advances. 
  • Strong communicator. Oncology care is provided by an entire medical team, so nurses need to be effective at communicating patient treatment plans to everyone involved. 
  • Compassionate. The ability to empathize with patients and caregivers in the face of a life-threatening illness is crucial. 
  • Resilient. Oncology nursing can take an emotional toll, so it’s important to have both a strong support system and interests outside of work to take care of yourself.
  • Problem solver. Whether they’re advising patients on how to cope with the side effects of treatment or helping them find transportation to their appointments, oncology nurses must continually identify and eliminate barriers to timely and quality care. 

Where You’ll Work

Oncology nurses work in a variety of settings. Your day-to-day tasks may vary based on both where you work and your specialty. Here are some common work settings and the role of oncology nurses who works there:

  • Hospitals: Coordinate care for patients of all ages and stages of treatment
  • Cancer centers: Provide treatment to individuals who have received a formal cancer diagnosis 
  • Clinics: Treat non-emergency problems or provide routine care 
  • Physician offices: Treat cancer patients with minimally invasive procedures and educate them on follow-up care 
  • Hospice centers: Care for patients with terminal cancers 
  • Palliative care centers: Relieve symptoms and improve the quality of life for those with more serious or advanced cancers 
  • Extended-care facilities: Provide treatment outside of a hospital setting to those with long-term illnesses. 
  • Home care: Care for patients and treat them in the comfort of their home rather than in a clinical setting. 

A Day in the Life of an Oncology Nurse

Since oncology nurses work across different settings, a typical day on the job can vary widely. Jaime Weimer, MSN, RN, AGCNS-BC, AOCNS, an oncology nursing specialist, describes a few day-in-the-life scenarios for oncology nurses: 

“Typically, oncology nurses work collaboratively with other healthcare providers to ensure the patient’s plan of care is authorized, scheduled, and ordered correctly. They serve as clinical coordinators or nurse navigators to provide education to patients and families and ensure they have all the information and resources they need to attend their treatment appointments. A nurse in this setting might also take phone calls from patients who have received treatment and have questions or concerns about their symptoms or side effects. 

Many oncology nurses work in an infusion department that is focused on administering chemotherapy or immunotherapy to patients.  This includes starting IVs, accessing central lines like PICCs or implanted ports, providing injections or infusion therapy, and monitoring for acute side effects or infusion reactions. They also serve as a resource for education on what to expect at home following treatment and provide information and education for patients on how to take their medications at home to manage side effects and when to call if they aren’t feeling well.

Finally, some oncology nurses also work in research, so a day on the job might include helping to screen, enroll, and collect clinical information for patients who are taking part in clinical trials. This may include performing detailed assessments and screenings, ensuring specific tests and diagnostics are ordered and performed, and ensuring the patient receives their treatment as indicated by the research protocol. Research nurses in oncology play a vital role in ensuring the protocol is followed and the data collected is accurate and timely.” 

Education to Become an Oncology Nurse

You’ll need to earn either an ADN or a BSN to become a registered nurse (RN) and pursue oncology as a specialty. Earning a BSN may lead to more leadership opportunities within a healthcare organization.

Associate Degree in Nursing

“An associate degree prepares nurses for entry-level positions following successful completion of the NCLEX examination and application approval for state nursing licensure,” says Weimer.

  • Prerequisites: A high school diploma or GED; high school biology and chemistry are strongly recommended
  • Core curriculum: Microbiology, nursing foundations, chemistry, communications, biology, statistics 
  • Clinical requirements: Students complete 700 clinical hours of work experience to earn their degree. Aspiring oncology nurses should aim to spend as many as possible in oncology settings.  
  • Time to complete: 2 years of full-time study

Bachelor of Science in Nursing

Weimer says a bachelor’s degree “provides a more robust curriculum that includes additional training in critical thinking, research appraisal, and professional practice leadership.”

“Many hospital systems encourage and prefer BSN-prepared nurses for specialty care units, such as oncology,” she says. “Roles that include additional responsibility and independence, such as nurse navigators, clinical coordinators, team leaders, and supervisory positions, will likely require a BSN as well as specialized clinical certification like the Oncology Certified Nurse (OCN) certification.”

  • Prerequisites: A high school diploma or GED; strong grades in science coursework, prior coursework in biology and chemistry, and volunteer experience are highly recommended.
  • Core curriculum: Psychology, sociology, public health, health policy, and healthcare administration. Weimer also recommends courses in business, writing and communication, ethics, and data analysis. 
  • Clinical requirements: 860 or more hours of hands-on experience. Aspiring oncology nurses should aim to spend as many of these hours as possible in oncology settings. 
  • Time to complete: 4 years of full-time study

Online Oncology Nursing Programs

There are many online nursing programs available for students who need a flexible schedule, like those with full-time jobs or family responsibilities. Students can do coursework online, but they’ll need to do all clinical and hands-on training in person.

There are also accelerated online programs in nursing for those who have already earned an ADN or a bachelor’s degree in another field. These programs can save you time and money because they let you apply some of your previous learning toward a BSN.

What to Look for in a School

Certain nursing programs may be a better fit than others. When you’re researching programs, look for the following:

  • Program accreditation. Check to see if the program is accredited by either the Accreditation Commission for Education in Nursing (ACEN) or the Commission on Collegiate Nursing Education (CCNE). If you enroll in a non-accredited program, you won’t be able to apply for federal financial aid or possibly take the National Council Licensure Examination (NCLEX-RN). A passing grade on the exam is required to apply for an RN license and get a nursing job.
  • Job placement and career counseling. Check to see if the school has strong relationships with local medical facilities or has an active alumni network.
  • A high first-time pass rate for students who took the NCLEX-RN. Look at student pass rates for the most recent academic year to get a better feel for how well the program will prepare you for the test.


State nursing boards license nurses in their states. To be licensed as an RN, you’ll first need to pass the NCLEX-RN.

The test is pass/fail and contains a variety of question types, including multiple-choice and fill-in-the-blank.

  • Format: Computerized, with questions tailored to each student by basing questions on your answer to the previous question. The test ends when the computer reaches a 95% certainty that you’ve either passed or failed.  
  • Knowledge tested: Four main topics: safe and effective care management, health promotion and maintenance, psychosocial integrity, and physiological integrity
  • Number of questions: 75 minimum and 265 maximum
  • Time: Up to six hours 
  • Test prep resources: Practice tests and prep courses can be found online.

After you receive official notice that you passed the exam, you can apply for licensure through your state’s nursing board. Most licensure applications require proof of graduation from an accredited nursing program, your NCLEX-RN test results and, in some cases, a background check.

Gain Experience

It’s common for recent nursing grads to gain work experience in general nursing before moving into a specialty like oncology.

“Jobs in inpatient units that care for general medical-surgical patients with cancer are a common place for new nursing graduates to get their start,” says Weimer. “Transitioning to units or departments that are dedicated to oncology care that treat critically ill patients or are providing intensive treatments may prefer nurses to have some experience before hiring them.”

It’s common for recent nursing grads to gain work experience in general nursing before moving into a specialty like oncology.

Weimer says that outpatient oncology areas “can be a challenging transition for new nurses, as the routine practice in these areas is not the focus of what is taught in nursing school. With the right preceptor and leader, new nurses can be successful in these areas but may need a longer orientation and training period to be fully independent in practice.”


Getting certified is optional, but it’s a great way to demonstrate your expertise. The professional recognition that comes with certification can also qualify you for more job opportunities and possibly lead to higher pay.

The basic certification for oncology nurses is the Oncology Certified Nurse (OCN) credential, but you’ll need to gain professional experience before you can earn it.

What It Is: A certification that demonstrates a high level of competency for caring for adults with cancer.

Who It’s For: Oncology nurses who want to distinguish themselves in the field and enhance their professional credentials.

Requirements: You must have:

  • Two years of work experience as an RN within the past four years
  • A minimum of 2,000 hours of adult oncology nursing practice
  • A minimum of 10 contact hours of oncology nursing continuing education within the past three years  

Exam and Prep: The computer-based exam has 165 multiple choice questions and takes up to three hours to complete. It covers:

  • Care continuum
  • Oncology nursing practice
  • Treatment modalities
  • Symptom management and palliative care
  • Oncologic emergencies
  • Psychosocial dimensions of care

To pass, you’ll need to answer at least 97 questions correctly. The Oncology Nursing Certification Corporation offers a test outline to prepare for the exam, plus review and prep courses.

Specialty Certifications

If you want to focus on one aspect of oncology nursing, there are specialty certifications you can earn as well:

  • Certified Pediatric Oncology Nurse (CPON): For nurses who have experience treating children with cancer 
  • Certified Pediatric Hematology Oncology Nurse (CPHON): For nurses who have experience treating children with blood cancers
  • Certified Breast Care Nurse (CBCN): For nurses who have treated patients with breast cancer
  • Blood and Marrow Transplant Certified Nurse (BMTCN): For nurses who have treated patients with cancers that require blood and marrow transplants
  • Advanced Oncology Certified Nurse (AOCN): For nurses who have deep experience and have taken a high number of continuing education courses. 

How Much Do Oncology Nurses Make?

According to the Bureau of Labor Statistics (BLS), RNs earn a median salary of $81,220. The BLS doesn’t differentiate between different types of nurses, but nurses who specialize tend to earn higher salaries.

Registered Nurses

National data

Median Salary: $81,220

Projected job growth: 5.6%

10th Percentile: $61,250

25th Percentile: $66,680

75th Percentile: $101,100

90th Percentile: $129,400

Projected job growth: 5.6%

State data

State Median Salary Bottom 10% Top 10%
Alabama $63,090 $48,820 $82,760
Alaska $102,260 $80,950 $127,280
Arizona $82,330 $66,040 $105,520
Arkansas $64,130 $37,630 $83,700
California $132,660 $84,700 $177,670
Colorado $82,430 $66,130 $107,260
Connecticut $95,210 $71,050 $119,600
Delaware $82,230 $64,100 $101,110
District of Columbia $98,970 $66,260 $135,260
Florida $77,710 $61,190 $100,060
Georgia $79,440 $60,400 $118,270
Hawaii $120,100 $76,640 $137,710
Idaho $77,940 $61,530 $100,440
Illinois $78,980 $62,180 $102,080
Indiana $73,290 $55,200 $95,600
Iowa $65,000 $56,330 $83,360
Kansas $66,460 $52,010 $93,120
Kentucky $75,800 $56,120 $98,540
Louisiana $73,180 $57,500 $95,540
Maine $77,340 $61,170 $100,910
Maryland $83,850 $64,680 $106,910
Massachusetts $98,520 $67,480 $154,160
Michigan $79,180 $64,270 $100,920
Minnesota $84,060 $65,500 $107,960
Mississippi $63,330 $49,980 $84,030
Missouri $71,460 $51,440 $94,340
Montana $76,550 $62,930 $98,970
Nebraska $74,990 $58,900 $93,230
Nevada $94,930 $74,200 $130,200
New Hampshire $80,550 $62,790 $104,270
New Jersey $98,090 $76,650 $118,150
New Mexico $81,990 $64,510 $106,300
New York $100,370 $64,840 $132,950
North Carolina $76,430 $59,580 $100,430
North Dakota $69,640 $60,780 $91,150
Ohio $76,810 $61,860 $98,380
Oklahoma $74,520 $53,560 $97,520
Oregon $106,680 $81,470 $131,210
Pennsylvania $78,740 $61,450 $101,450
Rhode Island $85,960 $65,260 $104,790
South Carolina $75,610 $52,620 $93,190
South Dakota $62,920 $51,240 $80,860
Tennessee $65,800 $51,270 $95,490
Texas $79,830 $61,950 $105,270
Utah $77,240 $61,850 $98,000
Vermont $77,230 $60,900 $101,570
Virginia $79,700 $61,970 $104,410
Washington $101,230 $77,460 $131,230
West Virginia $74,160 $47,640 $96,470
Wisconsin $79,750 $65,110 $100,820
Wyoming $77,730 $60,910 $102,010

Source: U.S. Bureau of Labor Statistics (BLS) 2022 median salary; projected job growth through 2032. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Job Outlook

The BLS predicts that job openings for registered nurses will grow 5.6% through 2032, which is close to the average growth rate for all occupations.

Although the BLS notes that job prospects for all nurses are good, it also says RNs with a specialty and/or a BSN may have a competitive edge when applying for positions.

“All nursing roles are in demand right now, including those in oncology,” says Weimer. “Oncology is an exciting and rapidly changing field. It provides numerous opportunities for nurses to explore various practice settings while still using all their skills and knowledge to continue to practice at the top of their licensure.”

Although the BLS notes that job prospects for all nurses are good, it also says RNs with a specialty and/or a BSN may have a competitive edge when applying for positions.

Professional Resources

Tapping into professional associations and other resources can help you advance your career by expanding your network of colleagues, helping you stay on top of developments in your field, and advancing your skills and expertise. Resources like these may help you navigate your career as you move forward or alert you to new positions.

Here are a few professional resources to check out:

Oncology Nursing Society: A professional networking association that holds conferences and provides resources to develop your career.

Clinical Journal of Oncology Nursing: A bimonthly peer-reviewed journal that aims to improve cancer patient care by publishing timely articles.

International Society of Nurses in Cancer Care: An international networking and leadership development organization that holds conferences and offers education and training.

The Oncology Nursing Podcast: A biweekly podcast produced by the Oncology Nursing Society that interviews the nation’s top oncology nurses and experts on topics related to treating patients with cancer.

mimi polner

Written and reported by:

Mimi Polner

Contributing Writer

jaime weimer

With professional insight from:

Jaime Weimer, MSN, RN, AGCNS-BC, AOCNS

Oncology Clinical Nurse Specialist, Oncology Nursing Society