Updated: July 9, 2026

APRN vs NP: What’s the difference?

APRNs and NPs hold advanced degrees and certifications in their areas of expertise. But there are differences.

nurse practitioner confers with advanced practice registered nurse on patient chart
nurse practitioner confers with advanced practice registered nurse on patient chart

Key Takeaways

  • All nurse practitioners (NPs) are advanced practice registered nurses (APRNs), but not all APRNs are NPs.
  • The main difference lies in specialization and job responsibilities; NPs focus on primary care in specific areas while APRNs can hold various roles.
  • To become an NP, one must earn an MSN or DNP and pass a certification exam; APRNs have distinct requirements based on their specialty.
  • Nurse practitioners typically choose a specialty before licensing, while other APRNs can select it after starting practice.

All nurse practitioners (NPs) are advanced practice registered nurses (APRNs), but not all APRNs are NPs. You can find both NPs and APRNs working in hospitals, clinics, specialty offices among other places. 

APRNs and NPs hold advanced degrees and certifications in their areas of expertise. They often have nurse leadership positions within hospitals or private practices and they earn higher salaries than registered nurses in the same specialties. 

What are the differences between APRNs and NPs? 

A nurse practitioner (NP) is a type of APRN. The other three types of APRNs are nurse midwives (NMs), clinical nurse specialists (CNSs), and certified registered nurse anesthetists (CRNAs).

NPs specialize in chosen areas of medicine, such as gerontology, women’s health or mental health. The primary difference between the two is not only specialization but the job responsibilities and duties they perform.

APRN and NP roles and responsibilities

Compare side by side: APRN vs NP duties and responsibilities

Nurse Practitioner

Nurse practitioner responsibilities may include providing these types of primary care tasks to patients:

  • Diagnose both acute and chronic illnesses and infections
  • Order and review diagnostic tests, such as EKGs and ultrasounds
  • Review and analyze patient data 
  • Create treatment plans
  • Perform physical assessments and in-office treatments
  • In certain states, they can prescribe medication and run their own practices. 
  • Since NPs are APRNs, some APRNs share the same roles and responsibilities.

Advanced Practice Registered Nurse

The other types of ARPNs are responsible for the following: 

  • Certified registered nurse anesthetists: Administer anesthesia and other medications, and monitor patients who are under anesthesia or are recovering from being under anesthesia.
  • Clinical nurse specialists: Develop healthcare practice policies and procedures, provide expert support and consulting to registered nurses. 
  • Nurse midwives: Provide prenatal and postnatal care, educate new parents on caring for newborns, deliver newborns and diagnose and treat sexually transmitted infections (STIs). 

Workplaces

NPs and APRNs can find work in a variety of healthcare settings, including: 

  • Hospitals
  • Schools
  • Community health clinics
  • Private practices
  • Birthing centers
  • Long-term care facilities
  • Healthcare companies
  • Nursing homes
  • Correctional facilities
  • Specialty clinics
  • Urgent care clinics

Nurse practitioner specialties

While APRNs also have the ability to specialize in administrative, clinical and practical areas, they can choose a specialty after they start practicing as an RN. Nurse practitioners are required to choose a specialty before they become licensed. NPs can specialize in: 

Family nursing: Provide care and counseling for all ages, from pediatric to elderly.

Psychiatry nursing: Give treatment to all ages for mental health disorders. 

Pediatric nursing: Provide care for children ages zero to 18 (most commonly).

Neonatal nursing: Provide advanced care to babies in the labor and delivery units and ICU. 

Adult gerontology nursing: Manage acute and primary care for adults, from young adults to seniors. 

Women’s health nursing: Give primary care with a focus on reproductive and gynecological health.

Similarly, clinical nurse specialists and certified registered nurse anesthetists can specialize in different areas. 

CNSs can choose to work with a specific set of the population, such as adults or children, or within a certain medical specialty, such as cardiology or oncology.

CRNAs can specialize in areas like pediatric, obstetric, cardiovascular or neurosurgical anesthesia, to name a few.

What degree does each job require?

All APRNs hold advanced degrees. 

To become a nurse practitioner, you’ll need to earn either a Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) degree. To get into a higher education program, most schools will require you to have earned a Bachelor’s in Nursing (BSN), but there are some that will accept associate degrees. 

Nurse midwives and CNSs must hold, at minimum, an MSN. 

CRNAs need to earn both an MSN and either a DNP or Doctor of Nurse Anesthesia Practice (DNAP). 

Licenses and certifications

To become an APRN, you need to be a registered nurse, first and foremost. Then, depending on what type of APRN you want to become, you’ll need to apply for a specific license and/or certification. 

To become an APRN, you need to be a registered nurse, first and foremost.

NP Requirements

NPs need to complete their MSN or DNP degree and then pass the certification exam for their chosen specialty. NP certifications are offered by:

After you’ve taken and passed your certification exam, you can apply to be licensed in the state you intend to practice. Licenses must be maintained and recertified every few years. In some states, you need to apply for a separate licensure in order to prescribe medication. 

APRN Requirements

Each type of APRN has their own license and certification requirements

To become a licensed CRNA, you have to take and pass the national certification exam that’s administered by the National Board of Certification for Registered Nurse Anesthetists (NBCRNA). This three-hour exam is taken on the computer and consists of 100 to 170 questions. You must have a doctoral degree and a current RN license in order to sit for the exam. 

Nurse midwives must take and pass a certification exam given by the American Midwifery Certification Board (AMCB). The exam is four hours long and consists of 175 multiple-choice questions. 

In order to become state certified, clinical nurse specialists must pass a certification exam from the American Association of Critical-Care Nurses in their desired specialty. Aspiring CNSs must have a certain number of direct care hours before they can sit for their certification exam. 

APRN and NP salaries

The U.S. Bureau of Labor Statistics cites the median annual salary for nurse practitioners as $132,300, with a strong job growth outlook of 40.1% through 2034.

The top earning nurse practitioners make up to $174,420, and the bottom 10% earn $101,340. Salaries by state for NPs are as follows:

Nurse Practitioners

National data

Median Salary: $132,300

Projected job growth: 40.1%

10th Percentile: $101,340

25th Percentile: $117,990

75th Percentile: $156,700

90th Percentile: $174,420

Projected job growth: 40.1%

State data

State Median Salary Bottom 10% Top 10%
Alabama $105,750 $86,300 $134,650
Alaska $155,170 $95,570 $207,490
Arizona $134,420 $104,400 $173,270
Arkansas $125,660 $99,420 $205,810
California $168,520 $120,340 $240,830
Colorado $132,930 $87,770 $170,310
Connecticut $138,470 $109,930 $173,810
Delaware $131,040 $97,450 $162,870
District of Columbia $135,880 $115,200 $180,300
Florida $129,510 $101,920 $163,600
Georgia $129,430 $99,160 $166,060
Hawaii $135,570 $106,450 $174,350
Idaho $132,540 $100,480 $169,710
Illinois $130,680 $102,440 $161,470
Indiana $128,830 $101,790 $155,260
Iowa $130,160 $107,990 $167,590
Kansas $126,650 $98,330 $158,080
Kentucky $122,870 $95,710 $162,960
Louisiana $125,600 $99,050 $159,570
Maine $130,260 $107,820 $166,740
Maryland $131,110 $99,920 $169,330
Massachusetts $142,440 $111,950 $207,710
Michigan $131,450 $101,640 $165,870
Minnesota $133,260 $98,950 $170,140
Mississippi $124,730 $98,780 $156,830
Missouri $129,930 $100,650 $162,060
Montana $137,210 $105,110 $166,940
Nebraska $132,130 $103,820 $161,990
Nevada $140,670 $85,380 $172,170
New Hampshire $137,550 $106,070 $166,240
New Jersey $159,310 $122,390 $183,420
New Mexico $137,520 $106,320 $175,020
New York $153,510 $112,730 $198,060
North Carolina $128,990 $103,530 $164,320
North Dakota $130,070 $103,490 $162,020
Ohio $124,870 $100,780 $154,680
Oklahoma $133,390 $99,490 $167,950
Oregon $155,680 $124,660 $194,070
Pennsylvania $130,140 $102,940 $163,720
Rhode Island $135,970 $111,420 $176,410
South Carolina $123,290 $97,080 $160,170
South Dakota $128,840 $103,080 $156,000
Tennessee $117,590 $82,790 $137,880
Texas $131,670 $96,880 $161,980
Utah $130,920 $102,980 $175,220
Vermont $134,740 $108,510 $167,610
Virginia $127,810 $99,990 $161,470
Washington $156,100 $122,420 $187,240
West Virginia $127,320 $100,220 $155,500
Wisconsin $131,980 $106,320 $166,260
Wyoming $132,200 $101,970 $165,250

Source: U.S. Bureau of Labor Statistics (BLS) 2025 median salary; projected job growth through 2034. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

And for certified nurse midwives:

Nurse Midwives

National data

Median Salary: $134,040

Projected job growth: 11.1%

10th Percentile: $93,620

25th Percentile: $116,510

75th Percentile: $157,400

90th Percentile: $188,320

Projected job growth: 11.1%

State data

State Median Salary Bottom 10% Top 10%
Alaska $133,430 $111,400 $175,290
Arizona $140,960 $101,160 $258,680
California $203,840 $140,970 $227,590
Colorado $137,610 $124,970 $161,460
Connecticut $130,790 $122,870 $147,440
Delaware $127,510 $102,680 $153,610
District of Columbia $101,450 $92,250 $150,640
Florida $127,460 $49,780 $146,590
Georgia $105,510 $86,290 $164,300
Hawaii $170,110 $125,720 $193,780
Illinois $120,840 $58,200 $156,920
Indiana $101,630 $101,630 $145,100
Iowa $131,360 $81,620 $158,930
Louisiana $119,280 $96,680 $134,640
Maine $133,270 $110,900 $144,730
Maryland $140,120 $127,340 $166,910
Massachusetts $159,800 $120,230 $204,000
Michigan $125,140 $104,370 $142,430
Minnesota $134,810 $110,050 $158,440
Missouri $130,220 $89,860 $154,560
Nebraska $138,880 $130,370 $138,880
New Hampshire $142,960 $78,680 $164,930
New Jersey $153,970 $134,400 $193,760
New Mexico $123,350 $61,430 $150,340
New York $144,510 $104,860 $177,240
North Carolina $126,040 $97,830 $155,340
North Dakota $72,630 $71,200 $163,860
Ohio $127,730 $105,110 $143,250
Oregon $146,900 $129,910 $161,180
Pennsylvania $119,990 $77,620 $158,520
Rhode Island $135,180 $117,100 $168,300
South Carolina $122,390 $90,880 $151,590
Tennessee $116,980 $93,620 $135,410
Texas $123,380 $90,260 $153,100
Utah $130,930 $59,340 $169,440
Vermont $151,030 $126,090 $169,170
Virginia $135,710 $108,110 $164,450
Washington $158,970 $73,320 $175,100
Wisconsin $133,070 $87,990 $156,490

Source: U.S. Bureau of Labor Statistics (BLS) 2025 median salary; projected job growth through 2034. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Finally, salaries for certified registered nurse anesthetists:

Nurse Anesthetists

National data

Median Salary: $236,590

Projected job growth: 8.6%

10th Percentile: $155,250

25th Percentile: $206,730

75th Percentile: $294,350

90th Percentile: $339,500

Projected job growth: 8.6%

State data

State Median Salary Bottom 10% Top 10%
Alabama $190,300 $101,450 $270,220
Alaska $341,210 $212,150 $366,160
Arizona $248,660 $228,390 $313,990
Arkansas $224,280 $87,120 $300,080
California $292,410 $200,530 $335,550
Colorado N/A N/A N/A
Connecticut $236,960 $101,520 $325,790
Florida $210,570 $125,680 $416,000
Georgia $224,630 $167,110 $303,900
Idaho $263,130 $216,820 $338,620
Illinois $286,830 $103,490 $335,610
Indiana N/A N/A N/A
Iowa $273,070 $124,470 $315,610
Kansas $212,090 $166,080 $243,000
Kentucky $222,520 $189,630 $289,230
Louisiana $222,130 $176,660 $304,640
Maine $247,470 $219,970 $336,050
Maryland $223,140 $81,970 $351,020
Massachusetts $295,550 $199,760 $391,170
Michigan $247,010 $220,840 $299,120
Minnesota $266,190 $221,970 $292,200
Mississippi $198,410 $177,110 $281,010
Missouri $242,630 $177,900 $362,800
Montana $277,380 $233,670 $325,620
Nebraska $246,730 $188,560 $331,660
New Hampshire $275,980 $231,560 $320,140
New Jersey $291,350 $229,130 $370,880
New Mexico $129,370 $64,560 $271,970
New York $321,030 $144,900 $342,480
North Carolina $224,610 $117,170 $323,640
North Dakota $244,240 $223,490 $287,480
Ohio $231,810 $148,690 $329,690
Oklahoma $156,830 $156,830 $296,200
Oregon $272,330 $205,180 $339,300
Pennsylvania $221,530 $155,250 $303,640
Rhode Island N/A N/A N/A
South Carolina $265,480 $210,100 $401,600
South Dakota $263,930 $194,200 $287,650
Tennessee $211,450 $167,480 $286,630
Texas $244,990 $169,350 $340,950
Utah $126,600 $93,350 $208,310
Vermont $283,060 $222,080 $310,160
Virginia $252,110 $174,210 $387,020
Washington $274,390 $218,640 $358,160
West Virginia $278,530 $226,300 $380,340
Wisconsin $273,170 $223,690 $320,630
Wyoming $255,250 $188,650 $399,220

Source: U.S. Bureau of Labor Statistics (BLS) 2025 median salary; projected job growth through 2034. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Compare median annual salaries for NPs, APRNs and related careers:

Career Median Annual Salary
Nurse Practitioners $132,300
Nurse Anesthetists $236,590
Nurse Midwives $134,040
Registered Nurses $97,550
Physician Assistants $135,880

Choosing to become a nurse practitioner over a different type of APRN is personal and depends on what specialty and responsibilities you’re most interested in. 

If you’re looking to provide primary care, becoming a nurse practitioner might be well suited for you. If you prefer a more administrative role in healthcare, a clinical nurse specialist may be a better fit. Those interested in monitoring anesthesia and other medications can go on to become certified registered nurse anesthetists. There is no one right, wrong or better choice—all of these roles can be very fulfilling emotionally, ethically and financially.