Updated: March 25, 2026

APRN vs NP: What’s the difference?

APRNs and NPs hold advanced degrees and certifications in their areas of expertise. But there are differences.

nurse practitioner confers with advanced practice registered nurse on patient chart
nurse practitioner confers with advanced practice registered nurse on patient chart

All nurse practitioners (NPs) are advanced practice registered nurses (APRNs), but not all APRNs are NPs. You can find both NPs and APRNs working in hospitals, clinics, specialty offices among other places. 

APRNs and NPs hold advanced degrees and certifications in their areas of expertise. They often have nurse leadership positions within hospitals or private practices and they earn higher salaries than registered nurses in the same specialties. 

What are the differences between APRNs and NPs? 

A nurse practitioner (NP) is a type of APRN. The other three types of APRNs are nurse midwives (NMs), clinical nurse specialists (CNSs), and certified registered nurse anesthetists (CRNAs).

NPs specialize in chosen areas of medicine, such as gerontology, women’s health or mental health. The primary difference between the two is not only specialization but the job responsibilities and duties they perform.

APRN and NP roles and responsibilities

Compare side by side: APRN vs NP duties and responsibilities

Nurse Practitioner

Nurse practitioner responsibilities may include providing these types of primary care tasks to patients:

  • Diagnose both acute and chronic illnesses and infections
  • Order and review diagnostic tests, such as EKGs and ultrasounds
  • Review and analyze patient data 
  • Create treatment plans
  • Perform physical assessments and in-office treatments
  • In certain states, they can prescribe medication and run their own practices. 
  • Since NPs are APRNs, some APRNs share the same roles and responsibilities.

Advanced Practice Registered Nurse

The other types of ARPNs are responsible for the following: 

  • Certified registered nurse anesthetists: Administer anesthesia and other medications, and monitor patients who are under anesthesia or are recovering from being under anesthesia.
  • Clinical nurse specialists: Develop healthcare practice policies and procedures, provide expert support and consulting to registered nurses. 
  • Nurse midwives: Provide prenatal and postnatal care, educate new parents on caring for newborns, deliver newborns and diagnose and treat sexually transmitted infections (STIs). 

Workplaces

NPs and APRNs can find work in a variety of healthcare settings, including: 

  • Hospitals
  • Schools
  • Community health clinics
  • Private practices
  • Birthing centers
  • Long-term care facilities
  • Healthcare companies
  • Nursing homes
  • Correctional facilities
  • Specialty clinics
  • Urgent care clinics

Nurse practitioner specialties

While APRNs also have the ability to specialize in administrative, clinical and practical areas, they can choose a specialty after they start practicing as an RN. Nurse practitioners are required to choose a specialty before they become licensed. NPs can specialize in: 

Family nursing: Provide care and counseling for all ages, from pediatric to elderly.

Psychiatry nursing: Give treatment to all ages for mental health disorders. 

Pediatric nursing: Provide care for children ages zero to 18 (most commonly).

Neonatal nursing: Provide advanced care to babies in the labor and delivery units and ICU. 

Adult gerontology nursing: Manage acute and primary care for adults, from young adults to seniors. 

Women’s health nursing: Give primary care with a focus on reproductive and gynecological health.

Similarly, clinical nurse specialists and certified registered nurse anesthetists can specialize in different areas. 

CNSs can choose to work with a specific set of the population, such as adults or children, or within a certain medical specialty, such as cardiology or oncology.

CRNAs can specialize in areas like pediatric, obstetric, cardiovascular or neurosurgical anesthesia, to name a few.

What degree does each job require?

All APRNs hold advanced degrees. 

To become a nurse practitioner, you’ll need to earn either a Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) degree. To get into a higher education program, most schools will require you to have earned a Bachelor’s in Nursing (BSN), but there are some that will accept associate degrees. 

Nurse midwives and CNSs must hold, at minimum, an MSN. 

CRNAs need to earn both an MSN and either a DNP or Doctor of Nurse Anesthesia Practice (DNAP). 

Licenses and certifications

To become an APRN, you need to be a registered nurse, first and foremost. Then, depending on what type of APRN you want to become, you’ll need to apply for a specific license and/or certification. 

To become an APRN, you need to be a registered nurse, first and foremost.

NP Requirements

NPs need to complete their MSN or DNP degree and then pass the certification exam for their chosen specialty. NP certifications are offered by:

After you’ve taken and passed your certification exam, you can apply to be licensed in the state you intend to practice. Licenses must be maintained and recertified every few years. In some states, you need to apply for a separate licensure in order to prescribe medication. 

APRN Requirements

Each type of APRN has their own license and certification requirements

To become a licensed CRNA, you have to take and pass the national certification exam that’s administered by the National Board of Certification for Registered Nurse Anesthetists (NBCRNA). This three-hour exam is taken on the computer and consists of 100 to 170 questions. You must have a doctoral degree and a current RN license in order to sit for the exam. 

Nurse midwives must take and pass a certification exam given by the American Midwifery Certification Board (AMCB). The exam is four hours long and consists of 175 multiple-choice questions. 

In order to become state certified, clinical nurse specialists must pass a certification exam from the American Association of Critical-Care Nurses in their desired specialty. Aspiring CNSs must have a certain number of direct care hours before they can sit for their certification exam. 

APRN and NP salaries

The U.S. Bureau of Labor Statistics cites the median annual salary for nurse practitioners as $129,210, with a strong job growth outlook of 40.1% through 2034.

The top earning nurse practitioners make up to $169,950, and the bottom 10% earn $97,960. Salaries by state for NPs are as follows:

Nurse Practitioners

National data

Median Salary: $129,210

Projected job growth: 40.1%

10th Percentile: $97,960

25th Percentile: $109,940

75th Percentile: $149,570

90th Percentile: $169,950

Projected job growth: 40.1%

State data

State Median Salary Bottom 10% Top 10%
Alabama $106,930 $85,410 $132,860
Alaska $145,450 $76,470 $199,990
Arizona $133,790 $84,740 $172,610
Arkansas $113,660 $95,160 $141,760
California $166,610 $124,330 $234,800
Colorado $129,750 $83,060 $165,970
Connecticut $138,960 $105,980 $169,850
Delaware $127,810 $103,280 $165,890
District of Columbia $131,380 $101,020 $171,220
Florida $129,010 $100,540 $155,490
Georgia $126,060 $99,920 $163,970
Hawaii $130,940 $101,430 $166,160
Idaho $128,940 $103,220 $166,400
Illinois $128,620 $102,280 $158,680
Indiana $128,280 $101,470 $161,150
Iowa $129,420 $102,150 $167,110
Kansas $124,690 $96,290 $161,010
Kentucky $113,870 $89,760 $149,350
Louisiana $125,980 $95,960 $156,030
Maine $125,040 $101,060 $160,260
Maryland $125,530 $92,860 $167,260
Massachusetts $138,890 $102,400 $205,230
Michigan $125,620 $101,200 $149,330
Minnesota $128,570 $96,720 $163,660
Mississippi $119,290 $92,720 $162,290
Missouri $126,370 $94,500 $151,010
Montana $133,640 $103,340 $163,160
Nebraska $127,930 $100,810 $161,800
Nevada N/A N/A N/A
New Hampshire $132,440 $106,160 $160,750
New Jersey $149,620 $65,130 $173,320
New Mexico $138,440 $80,890 $187,840
New York $145,390 $106,640 $194,470
North Carolina $125,020 $100,120 $158,440
North Dakota $123,220 $92,650 $158,890
Ohio $126,740 $98,380 $154,280
Oklahoma $126,670 $78,090 $165,280
Oregon $144,600 $103,570 $186,380
Pennsylvania $127,400 $101,370 $159,920
Rhode Island $130,710 $111,590 $176,010
South Carolina $116,240 $62,220 $145,560
South Dakota $122,600 $99,980 $153,600
Tennessee $108,420 $61,530 $133,120
Texas $129,880 $96,140 $165,530
Utah $125,700 $95,570 $172,850
Vermont $129,740 $100,210 $163,390
Virginia $124,210 $85,020 $155,800
Washington $140,220 $107,700 $177,770
West Virginia $121,640 $93,350 $149,910
Wisconsin $128,580 $107,010 $161,600
Wyoming $127,750 $83,390 $161,340

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

And for certified nurse midwives:

Nurse Midwives

National data

Median Salary: $128,790

Projected job growth: 11.1%

10th Percentile: $74,670

25th Percentile: $104,260

75th Percentile: $146,520

90th Percentile: $177,040

Projected job growth: 11.1%

State data

State Median Salary Bottom 10% Top 10%
Alaska $130,030 $108,190 $179,930
Arizona $135,590 $102,980 N/A
California $196,700 $111,800 $226,840
Colorado $132,670 $47,960 $154,750
Connecticut $124,530 $109,110 $147,350
Delaware $99,060 $79,210 $139,790
District of Columbia $106,580 $89,010 $145,350
Florida $115,440 $45,930 $141,010
Georgia $125,830 $97,760 $159,250
Idaho $89,870 $20,780 $138,540
Illinois $114,420 $52,660 $143,630
Indiana $129,010 $110,770 $165,000
Iowa $136,450 $82,950 $204,960
Louisiana $95,420 $86,180 $131,150
Maine $132,920 $106,670 $163,810
Maryland $129,910 $116,190 $159,650
Massachusetts $155,710 $127,950 $225,190
Michigan $116,810 $94,320 $142,440
Minnesota $127,180 $85,560 $157,660
Missouri $134,970 $111,590 $163,960
Nebraska $133,890 $129,440 $133,940
New Hampshire $135,860 $75,690 $147,970
New Jersey $135,680 $106,630 $161,010
New Mexico $118,650 $37,290 $144,930
New York $137,860 $108,970 $173,130
North Carolina $121,490 $94,310 $143,100
Ohio $121,720 $105,790 $148,630
Oregon $123,080 $69,340 $159,480
Pennsylvania $107,740 $74,670 $152,890
Rhode Island $127,480 $114,400 $161,890
South Carolina $118,100 $82,920 $135,180
Tennessee $97,380 $89,710 $130,780
Texas $111,190 $80,890 $146,030
Utah $138,020 $78,270 $179,250
Vermont $140,240 $119,470 $171,620
Virginia $139,770 $89,290 $160,430
Washington $145,000 $105,990 $205,640
Wisconsin $135,360 $91,500 $161,450

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Finally, salaries for certified registered nurse anesthetists:

Nurse Anesthetists

National data

Median Salary: $223,210

Projected job growth: 8.6%

10th Percentile: $137,230

25th Percentile: $187,110

75th Percentile: N/A

90th Percentile: N/A

Projected job growth: 8.6%

State data

State Median Salary Bottom 10% Top 10%
Alabama $179,160 $97,890 N/A
Alaska N/A $189,840 N/A
Arizona $228,690 $218,420 N/A
Arkansas $134,230 $83,220 $218,140
California N/A $59,990 N/A
Colorado $207,120 $71,990 N/A
Connecticut $227,930 $103,740 N/A
Delaware $236,800 $123,970 N/A
Florida $197,940 $128,970 N/A
Georgia $221,190 $184,040 N/A
Illinois N/A $113,380 N/A
Indiana $233,200 $167,530 N/A
Iowa $229,950 $204,630 N/A
Kansas $182,770 $148,420 $236,790
Kentucky $212,430 $181,360 N/A
Louisiana $225,440 $196,200 N/A
Maine $229,900 $215,240 N/A
Maryland $167,740 $52,940 $237,250
Massachusetts N/A $228,800 N/A
Michigan $234,520 $187,110 N/A
Minnesota N/A $214,190 N/A
Mississippi $197,490 $163,330 N/A
Missouri $221,550 $166,660 N/A
Montana N/A N/A N/A
Nebraska $231,020 $165,860 N/A
New Hampshire N/A $214,250 N/A
New Jersey N/A $198,160 N/A
New Mexico $214,810 $103,710 N/A
New York N/A $174,120 N/A
North Carolina $226,460 $95,590 N/A
North Dakota $232,420 $210,250 N/A
Ohio $216,350 $116,800 N/A
Oklahoma $151,470 $151,470 N/A
Oregon N/A $159,770 N/A
Pennsylvania $217,670 $183,060 N/A
Rhode Island $131,390 $65,740 N/A
South Carolina $225,800 $183,040 N/A
South Dakota $223,650 $186,800 N/A
Tennessee $203,400 $137,240 $229,510
Texas $227,580 $178,330 N/A
Utah $122,040 $89,990 $201,520
Vermont N/A $214,290 N/A
Virginia $199,960 $114,880 N/A
Washington N/A $211,170 N/A
West Virginia N/A $197,680 N/A
Wisconsin N/A $209,550 N/A
Wyoming $181,470 $177,090 N/A

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Compare median annual salaries for NPs, APRNs and related careers:

Career Median Annual Salary
Nurse Practitioners $129,210
Nurse Anesthetists $223,210
Nurse Midwives $128,790
Registered Nurses $93,600
Physician Assistants $133,260

Choosing to become a nurse practitioner over a different type of APRN is personal and depends on what specialty and responsibilities you’re most interested in. 

If you’re looking to provide primary care, becoming a nurse practitioner might be well suited for you. If you prefer a more administrative role in healthcare, a clinical nurse specialist may be a better fit. Those interested in monitoring anesthesia and other medications can go on to become certified registered nurse anesthetists. There is no one right, wrong or better choice—all of these roles can be very fulfilling emotionally, ethically and financially.


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